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Symbol
Name
ID
Stat3
signal transducer and activator of transcription 3
MGI:103038
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Frontal bossing
Craniosynostosis
Interphalangeal joint erosions
Swan neck-like deformities of the fingers
Joint swelling
Osteomyelitis
Joint hypermobility
Joint stiffness
Recurrent fractures
Scoliosis
Osteopenia
Arthritis
Rheumatoid arthritis
Polyarticular arthritis
Digital flexor tenosynovitis
Disease(s) Associated with STAT3
Behcet's disease
hyper IgE recurrent infection syndrome 1
rheumatoid arthritis

Mouse Phenotypes
abnormal bone structure
decreased trabecular bone thickness
abnormal bone ossification
Availability Mouse Genotype
Stat3tm1Aki/Stat3tm2Aki
Tg(Col1a1-cre)1Kry/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory