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Symbol Name ID |
Sox2
SRY (sex determining region Y)-box 2 MGI:98364 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Tracheoesophageal fistula |
| Disease(s) Associated with SOX2 | |
| syndromic microphthalmia 3 |
| Mouse Phenotypes | respiratory system phenotype |
absent respiratory motile cilia |
tracheoesophageal fistula |
abnormal epiglottis morphology |
increased lung adenocarcinoma incidence |
abnormal lung morphology |
abnormal lung epithelium morphology |
abnormal bronchiole epithelium morphology |
absent club cells |
bronchiolar epithelial hyperplasia |
bronchial epithelial hyperplasia |
abnormal respiratory mucosa goblet cell morphology |
absent respiratory mucosa goblet cells |
lung epithelium hyperplasia |
respiratory distress |
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| Availability | Mouse Genotype | |||||||||||||||
| Sox2tm1Lpev/Sox2tm2Lpev | ||||||||||||||||
| Sox2tm2Lpev/Sox2tm3Lpev | * | |||||||||||||||
| Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+ (conditional) |
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| Sox2tm1.1Lan/Sox2tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 (conditional) |
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| Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sor+ Tg(Sftpc-cre)1Blh/0 (conditional) |
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| Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sor+ Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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