Symbol
Name
ID

Fas
Fas cell surface death receptor
MGI:95484

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes

Sinusitis

Chronic sinusitis

Pulmonary edema

Recurrent pneumonia

Asthma

Recurrent respiratory infections

Recurrent bronchopulmonary infections

Recurrent lower respiratory tract infections

Pleuritis

Pneumothorax

Pulmonary fibrosis

Pulmonary infiltrates

Hemoptysis

Bronchiectasis

Decreased forced expiratory flow 25-75%

Reduced forced expiratory volume in one second

Reduced forced vital capacity

Airway obstruction

Chronic lung disease

Hyperpolarized transepithelial nasal potential difference

Disease(s) Associated with FAS

autoimmune lymphoproliferative syndrome

cystic fibrosis

pre-eclampsia

systemic lupus erythematosus

Mouse Phenotypes		lung inflammation	alveolitis	pulmonary fibrosis	abnormal airway responsiveness
Availability	Mouse Genotype	lung inflammation	alveolitis	pulmonary fibrosis	abnormal airway responsiveness
	Fas^lpr/Fas^lpr
	Fas^tm1Cgn/Fas^tm1Cgn Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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