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Symbol
Name
ID
Klf5
Kruppel-like transcription factor 5
MGI:1338056
Phenotype annotations related to respiratory system
Darker colors indicate more annotations

Mouse Phenotypes
pulmonary vascular congestion
pulmonary edema
pulmonary alveolar edema
abnormal lung development
abnormal lung saccule morphology
thick lung-associated mesenchyme
abnormal type I pneumocyte morphology
decreased type I pneumocyte number
abnormal type II pneumocyte morphology
absent alveolar lamellar bodies
increased wet-to-dry lung weight ratio
abnormal pulmonary alveolus morphology
increased pulmonary respiratory rate
respiratory distress
abnormal surfactant secretion
Availability Mouse Genotype
Klf5tm1Jaw/Klf5tm1Jaw
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0  (conditional)
Klf5tm2.1Rng/Klf5tm2.1Rng
Tg(Postn-cre)1Sjc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory