|
Symbol Name ID |
Sftpb
surfactant associated protein B MGI:109516 |
| Darker colors indicate more annotations |
| Human Phenotypes | Pulmonary edema |
Misalignment of the pulmonary veins |
Pulmonary arterial hypertension |
Acute infectious pneumonia |
Recurrent pneumonia |
Hypoxemia |
Crackles |
Apnea |
Dyspnea |
Exertional dyspnea |
Respiratory distress |
Tachypnea |
Absent bronchoalveolar dimeric surfactant-protein B |
Absent bronchoalveolar surfactant-protein C |
Intraalveolar phospholipid accumulation |
Spontaneous pneumothorax |
Type II pneumocyte hyperplasia |
Desquamative interstitial pneumonitis |
Honeycomb lung |
Interstitial pneumonitis |
Nonspecific interstitial pneumonia |
Pulmonary fibrosis |
Crazy paving pattern |
Cystic pattern on pulmonary HRCT |
Nodular pattern on pulmonary HRCT |
Interlobular septal thickening |
Intralobular septal thickening |
Reticular pattern on pulmonary HRCT |
Usual interstitial pneumonia |
Paraseptal emphysema |
Atelectasis |
Ground-glass opacification |
Bronchial wall thickening |
Bronchiectasis |
Decreased DLCO |
Reduced forced expiratory volume in one second |
Reduced forced vital capacity |
Restrictive ventilatory defect |
Chronic pulmonary obstruction |
Cough |
Respiratory insufficiency |
Neonatal respiratory distress |
Respiratory failure |
Respiratory failure requiring assisted ventilation |
| Disease(s) Associated with SFTPB | ||||||||||||||||||||||||||||||||||||||||||||
| chronic obstructive pulmonary disease | ||||||||||||||||||||||||||||||||||||||||||||
| newborn respiratory distress syndrome | ||||||||||||||||||||||||||||||||||||||||||||
| pulmonary alveolar proteinosis |
| Mouse Phenotypes | abnormal type II pneumocyte morphology |
absent alveolar lamellar bodies |
abnormal pulmonary alveolus morphology |
atelectasis |
decreased total lung capacity |
respiratory distress |
decreased lung compliance |
respiratory failure |
abnormal surfactant physiology |
abnormal surfactant composition |
abnormal surfactant secretion |
|
| Availability | Mouse Genotype | |||||||||||
| Sftpbtm1Jaw/Sftpbtm1Jaw | ||||||||||||
| Sftpbtm1Jaw/Sftpb+ | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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