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Symbol
Name
ID
Zic3
zinc finger protein of the cerebellum 3
MGI:106676
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Pulmonary artery atresia
Partial anomalous pulmonary venous return
Total anomalous pulmonary venous return
Tracheoesophageal fistula
Respiratory distress
Bilateral trilobed lung
Pulmonary hypoplasia
Laryngeal atresia
Disease(s) Associated with ZIC3
situs inversus
visceral heterotaxy
X-linked VACTERL association

Mouse Phenotypes
left pulmonary isomerism
lung situs inversus
right pulmonary isomerism
abnormal cricoid cartilage morphology
abnormal lung position or orientation
Availability Mouse Genotype
Zic3tm1Bca/Zic3tm1Bca
Zic3tm1Jwb/Zic3tm1Jwb
Zic3tm1Bca/Zic3+
Zic3tm1Bca/Y
Zic3tm1Jwb/Y
Zic3tm2.1Jwb/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory