|
Symbol Name ID |
Tnf
tumor necrosis factor MGI:104798 |
| Darker colors indicate more annotations |
| Human Phenotypes | Sinusitis |
Chronic sinusitis |
Pleural effusion |
Pulmonary edema |
Pulmonary arterial hypertension |
Recurrent pneumonia |
Asthma |
Recurrent respiratory infections |
Recurrent bronchopulmonary infections |
Recurrent lower respiratory tract infections |
Bronchoconstriction |
Respiratory distress |
Pleuritis |
Pneumothorax |
Abnormal pulmonary interstitial morphology |
Pulmonary fibrosis |
Hemoptysis |
Bronchiectasis |
Abnormality of the upper respiratory tract |
Decreased forced expiratory flow 25-75% |
Reduced forced expiratory volume in one second |
Reduced forced vital capacity |
Airway hyperresponsiveness |
Airway obstruction |
Chronic pulmonary obstruction |
Chronic lung disease |
Hyperpolarized transepithelial nasal potential difference |
Respiratory insufficiency |
| Disease(s) Associated with TNF | ||||||||||||||||||||||||||||
| asthma | ||||||||||||||||||||||||||||
| atopic dermatitis | ||||||||||||||||||||||||||||
| beta thalassemia | ||||||||||||||||||||||||||||
| chronic obstructive pulmonary disease | ||||||||||||||||||||||||||||
| cystic fibrosis | ||||||||||||||||||||||||||||
| Gaucher's disease | ||||||||||||||||||||||||||||
| leprosy | ||||||||||||||||||||||||||||
| malaria | ||||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||||
| pre-eclampsia | ||||||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | abnormal lung vasculature morphology |
lung hemorrhage |
lung inflammation |
alveolitis |
interstitial pneumonia |
abnormal respiratory system morphology |
abnormal lung morphology |
abnormal pulmonary alveolus epithelium morphology |
abnormal type II pneumocyte morphology |
abnormal pulmonary alveolar system morphology |
abnormal pulmonary alveolus wall morphology |
abnormal pulmonary interalveolar septum morphology |
thick pulmonary interalveolar septum |
emphysema |
pulmonary fibrosis |
abnormal respiration |
tachypnea |
respiratory distress |
respiratory failure |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Tnftm1Ljo/Tnftm1Ljo | ||||||||||||||||||||
| Tg(SFTPC-rtTA,tetO-Tnf)320-1Gwho/0 | ||||||||||||||||||||
| Tg(SFTPC-Tnf)2Pva/0 | ||||||||||||||||||||
| Tg(Tek-Tnf*)5382Mcla/0 | ||||||||||||||||||||
| Tg(Myh6-Tnf)1Brgi/? | ||||||||||||||||||||
| Tg(Myh6-Tnf)2Brgi/? | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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