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Symbol
Name
ID
Lta
lymphotoxin A
MGI:104797
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Sinusitis
Chronic sinusitis
Recurrent pneumonia
Asthma
Recurrent respiratory infections
Recurrent bronchopulmonary infections
Recurrent lower respiratory tract infections
Bronchoconstriction
Pneumothorax
Hemoptysis
Bronchiectasis
Abnormality of the upper respiratory tract
Decreased forced expiratory flow 25-75%
Reduced forced expiratory volume in one second
Reduced forced vital capacity
Airway hyperresponsiveness
Airway obstruction
Chronic lung disease
Hyperpolarized transepithelial nasal potential difference
Disease(s) Associated with LTA
asthma
cystic fibrosis
leprosy

Mouse Phenotypes
increased bronchoconstrictive response
lung inflammation
increased pulmonary ventilation
Availability Mouse Genotype
Ltahlb382/Ltahlb382
Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory