Symbol
Name
ID

Vegfa
vascular endothelial growth factor A
MGI:103178

Phenotype annotations related to respiratory system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Pleural effusion	Pulmonary edema	Decreased DLCO
Disease(s) Associated with VEGFA	Pleural effusion	Pulmonary edema	Decreased DLCO
multiple myeloma
pre-eclampsia
pseudoxanthoma elasticum

Mouse Phenotypes

respiratory system phenotype

decreased pulmonary endothelial cell surface

aorta pulmonary collateral arteries

abnormal lung vasculature morphology

abnormal pulmonary circulation

decreased mesenchymal cell proliferation involved in lung development

pulmonary edema

lung inflammation

abnormal lung morphology

abnormal lung development

abnormal lung saccule morphology

abnormal lung epithelium morphology

abnormal pulmonary acinus morphology

atelectasis

thick pulmonary interalveolar septum

emphysema

pale lung

abnormal respiratory system physiology

respiratory distress

abnormal lung compliance

Availability

Mouse Genotype

Vegfa^tm1Pec/Vegfa^tm1Pec

Vegfa^tm2Pec/Vegfa^tm2Pec

Vegfa^tm4Pec/Vegfa^tm4Pec

Vegfa^tm2Gne/Vegfa^tm2Gne
Tg(SFTPC-cre)#Mliu/0 (conditional)

Vegfa^tm2Gne/Vegfa^tm2Gne
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0 (conditional)

Vegfa^tm2Gne/Vegfa⁺
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23