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Symbol
Name
ID

Cav1
caveolin 1, caveolae protein
MGI:102709

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes	Pulmonary arterial medial hypertrophy	Pulmonary aterial intimal fibrosis	Elevated pulmonary artery pressure	Pulmonary arterial hypertension	Pulmonary arterial hypertension with lack of acute response to NO challenge	Increased pulmonary vascular resistance	Pulmonary artery vasoconstriction	Dyspnea	Exertional dyspnea	Cough
Disease(s) Associated with CAV1
primary pulmonary hypertension

Mouse Phenotypes

abnormal pulmonary endothelial cell surface

abnormal lung vasculature morphology

pulmonary hyperemia

increased lung endothelial cell proliferation

pulmonary edema

lung inflammation

abnormal lung morphology

abnormal type II pneumocyte morphology

pulmonary interstitial fibrosis

thick pulmonary interalveolar septum

abnormal pulmonary alveolar parenchyma morphology

abnormal pulmonary elastic fiber morphology

increased lung elastance

increased airway resistance

abnormal respiratory mechanics

decreased lung compliance

Availability

Mouse Genotype

Cav1^tm1Kur/Cav1^tm1Kur

Cav1^tm1Mls/Cav1^tm1Mls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23