|
Symbol Name ID |
Trp53
transformation related protein 53 MGI:98834 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Choriocarcinoma |
Testicular neoplasm |
Prostate neoplasm |
Prostate cancer |
Ovarian neoplasm |
Ovarian carcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with TP53 | |||||||
| colorectal cancer | |||||||
| Li-Fraumeni syndrome | |||||||
| Li-Fraumeni syndrome 1 | |||||||
| pancreatic cancer | |||||||
| prostate cancer |
| Mouse Phenotypes | reproductive system phenotype |
abnormal male germ cell apoptosis |
ovary cyst |
ovary degeneration |
decreased testis weight |
small testis |
testis hypoplasia |
increased ovary tumor incidence |
increased testis tumor incidence |
increased testicular teratoma incidence |
increased endometrial carcinoma incidence |
increased reproductive system tumor incidence |
abnormal endometrium morphology |
abnormal spermatogenesis |
abnormal corpus epididymis morphology |
small gonad |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Trp53tm1.1Tldo/Trp53tm1.1Tldo | |||||||||||||||||
| Trp53tm1.2Awbr/Trp53tm1.2Awbr | |||||||||||||||||
| Trp53tm1Tyj/Trp53tm1Tyj | |||||||||||||||||
| Trp53tm2.1Kasa/Trp53tm2.1Kasa | * | ||||||||||||||||
| Trp53tm2.1Thst/Trp53tm2.1Thst | |||||||||||||||||
| Trp53tm1.2Awbr/Trp53+ | |||||||||||||||||
| Trp53tm1Brd/Trp53tm8Xu | |||||||||||||||||
| Trp53tm1Ldo/Trp53+ | |||||||||||||||||
| Trp53tm1Tyj/Trp53tm1.1Umol | |||||||||||||||||
| Trp53tm1Tyj/Trp53tm2.1Umol | |||||||||||||||||
| Trp53tm2Thst/Trp53tm2.1Thst | |||||||||||||||||
| Tg(Trp53)1Srn/0 | * | ||||||||||||||||
| Tg(Trp53A135V)L3Ber/0 | |||||||||||||||||
| Trp53tm1Brn/Trp53tm1Brn (conditional) | |||||||||||||||||
| Pgrtm2(cre)Lyd/Pgr+ Trp53tm1Brn/Trp53tm1Brn (conditional) |
* | ||||||||||||||||
| Trp53tm1Brn/Trp53tm1Brn Tg(Cdh16-cre)91Igr/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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