|
Symbol Name ID |
Lhcgr
luteinizing hormone/choriogonadotropin receptor MGI:96783 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Female hypogonadism |
Hypergonadotropic hypogonadism |
Male hypogonadism |
Abnormal external genitalia |
Hypospadias |
Micropenis |
Long penis |
Hypoplasia of the Leydig cells |
Decreased testicular size |
Macroorchidism |
Cryptorchidism |
Testicular gonadoblastoma |
Male pseudohermaphroditism |
Ambiguous genitalia |
Abnormal internal genitalia |
Abnormal vas deferens morphology |
Aplasia of the uterus |
Primary amenorrhea |
Secondary amenorrhea |
Oligozoospermia |
Male infertility |
| Disease(s) Associated with LHCGR | |||||||||||||||||||||
| familial male-limited precocious puberty | |||||||||||||||||||||
| Leydig cell hypoplasia |
| Mouse Phenotypes | reproductive system phenotype |
oligozoospermia |
increased male germ cell apoptosis |
abnormal anogenital distance |
bulbourethral gland hypoplasia |
abnormal prostate gland morphology |
small prostate gland anterior lobe |
increased prostate gland weight |
enlarged prostate gland |
small prostate gland |
prostate gland hypoplasia |
decreased seminal vesicle weight |
increased seminal vesicle weight |
enlarged seminal vesicle |
small seminal vesicle |
seminal vesicle hypoplasia |
absent endometrial glands |
decreased endometrial gland number |
abnormal ovary morphology |
absent corpus luteum |
absent mature ovarian follicles |
impaired ovarian folliculogenesis |
decreased ovary weight |
small ovary |
abnormal seminiferous tubule morphology |
small seminiferous tubules |
abnormal adult Leydig cell differentiation |
decreased Leydig cell number |
absent Leydig cells |
increased Leydig cell number |
decreased testis weight |
small testis |
testis hypoplasia |
cryptorchism |
prostate gland inflammation |
decreased ovary secretion |
decreased testes secretion |
reproductive system inflammation |
epididymis inflammation |
small penis |
abnormal female reproductive system morphology |
ambiguous external female genitalia |
abnormal uterus morphology |
thin endometrium |
thin myometrium |
thin uterine horn |
thin uterus |
abnormal vagina development |
abnormal vagina orifice morphology |
arrest of spermatogenesis |
abnormal male reproductive system morphology |
scrotum hypoplasia |
external male genitalia atrophy |
abnormal epididymis morphology |
abnormal caput epididymis morphology |
abnormal cauda epididymis morphology |
abnormal epididymis epithelium morphology |
decreased epididymis weight |
increased epididymis weight |
small epididymis |
epididymis hypoplasia |
vas deferens hypoplasia |
delayed vaginal opening |
early sexual maturation |
abnormal reproductive system physiology |
absent estrus |
absent estrous cycle |
female infertility |
male infertility |
reduced male fertility |
abnormal ejaculation |
decreased epididymal cell proliferation |
abnormal sperm physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lhcgrtm1Hht/Lhcgrtm1Hht | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lhcgrtm1Zmlei/Lhcgrtm1Zmlei | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lhcgrtm1.1Pnara/Lhcgr+ | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/21/2024 MGI 6.23 |
|
|
|
||
Analysis Tools