Symbol
Name
ID

Mcm9
minichromosome maintenance 9 homologous recombination repair factor
MGI:1918817

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Primary amenorrhea
Disease(s) Associated with MCM9	Primary amenorrhea
ovarian dysgenesis 4

Mouse Phenotypes

reproductive system phenotype

abnormal female germ cell morphology

decreased oocyte number

oligozoospermia

abnormal spermatogonia morphology

decreased male germ cell number

decreased primordial germ cell number

arrest of male meiosis

abnormal male germ cell apoptosis

abnormal ovarian follicle number

decreased primordial ovarian follicle number

ovary hyperplasia

abnormal seminiferous tubule morphology

small testis

increased ovary tumor incidence

premature ovarian failure

female infertility

Availability

Mouse Genotype

Mcm9^{Gt(AW0655)Wtsi}/Mcm9^{Gt(AW0655)Wtsi}

Mcm9^Gt(XG743)Byg/Mcm9^Gt(XG743)Byg

Mcm9^tm1.1Geno/Mcm9^tm1.1Geno

Mcm9^{Gt(AW0655)Wtsi}/Mcm9^Gt(XG743)Byg

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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