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Symbol Name ID |
Fbxw7
F-box and WD-40 domain protein 7 MGI:1354695 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cryptorchidism |
| Disease(s) Associated with FBXW7 | |
| developmental delay, hypotonia, and impaired language |
| Mouse Phenotypes | oligozoospermia |
decreased male germ cell number |
increased male germ cell apoptosis |
abnormal male germ cell physiology |
abnormal seminiferous tubule epithelium morphology |
abnormal Sertoli cell barrier morphology |
abnormal Sertoli cell morphology |
decreased Sertoli cell number |
ectopic Sertoli cells |
seminiferous tubule degeneration |
abnormal testis development |
decreased testis weight |
small testis |
testicular atrophy |
testis degeneration |
arrest of spermatogenesis |
abnormal epididymis morphology |
decreased epididymis weight |
small epididymis |
decreased litter size |
male infertility |
reduced male fertility |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Fbxw7tm1Iaai/Fbxw7tm1Iaai Tg(Amh-cre)8815Reb/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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