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Symbol
Name
ID

Nbn
nibrin
MGI:1351625

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Prostate cancer	Dysgerminoma	Ovarian papillary adenocarcinoma	Premature ovarian insufficiency
Disease(s) Associated with NBN	Prostate cancer	Dysgerminoma	Ovarian papillary adenocarcinoma	Premature ovarian insufficiency
Nijmegen breakage syndrome
ovarian cancer
prostate cancer

Mouse Phenotypes		reproductive system phenotype	decreased oocyte number	absent oocytes	absent ovarian follicles	small ovary	ovary degeneration	increased prostate intraepithelial neoplasia incidence	increased Leydig cell tumor incidence	increased gonad tumor incidence	female infertility
Availability	Mouse Genotype	reproductive system phenotype	decreased oocyte number	absent oocytes	absent ovarian follicles	small ovary	ovary degeneration	increased prostate intraepithelial neoplasia incidence	increased Leydig cell tumor incidence	increased gonad tumor incidence	female infertility
	Nbn^tm1Jpt/Nbn^tm1Jpt	*
	Nbn^tm1Xu/Nbn^tm1Xu
	Nbn^tm1Zqw/Nbn⁺
	Nbn^tm1Nus/Nbn^tm2Nus Tg(Spo11-cre)D5Mpel/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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