Symbol Name ID |
Fanca
Fanconi anemia, complementation group A MGI:1341823 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Hypogonadism |
Hypergonadotropic hypogonadism |
Hypospadias |
Abnormal preputium morphology |
Abnormal testis morphology |
Absent testis |
Cryptorchidism |
Dysgerminoma |
Ovarian carcinoma |
Ovarian papillary adenocarcinoma |
Abnormality of the uterus |
Cervix cancer |
Bicornuate uterus |
Azoospermia |
Decreased fertility in males |
Male infertility |
Disease(s) Associated with FANCA | ||||||||||||||||
cervical cancer | ||||||||||||||||
Fanconi anemia | ||||||||||||||||
Fanconi anemia complementation group A | ||||||||||||||||
ovarian cancer | ||||||||||||||||
pancreatic cancer |
Mouse Phenotypes | ovary hemorrhage |
decreased germ cell number |
abnormal male meiosis |
increased male germ cell apoptosis |
abnormal ovary morphology |
decreased mature ovarian follicle number |
absent mature ovarian follicles |
small ovary |
ovary hypoplasia |
ovary cyst |
small seminiferous tubules |
seminiferous tubule degeneration |
increased Leydig cell number |
decreased testis weight |
small testis |
early reproductive senescence |
abnormal spermatogenesis |
small gonad |
reduced female fertility |
decreased litter size |
reduced male fertility |
|
Availability | Mouse Genotype | |||||||||||||||||||||
Fancatm1.1Wong/Fancatm1.1Wong | ! | ! | ||||||||||||||||||||
Fancatm1Faw/Fancatm1Faw | ||||||||||||||||||||||
Fancatm1Wong/Fancatm1Wong | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/14/2024 MGI 6.23 |
|
|