Symbol
Name
ID

Rfx2
regulatory factor X, 2 (influences HLA class II expression)
MGI:106583

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

reproductive system phenotype

abnormal sperm axoneme morphology

azoospermia

abnormal acrosome morphology

abnormal acrosome assembly

detached acrosome

abnormal spermatid morphology

abnormal manchette morphology

ectopic manchette

multinucleated giant male germ cells

increased male germ cell apoptosis

abnormal ectoplasmic specialization morphology

Leydig cell hypertrophy

increased Leydig cell number

small testis

abnormal spermatogenesis

abnormal spermiogenesis

arrest of spermiogenesis

arrest of spermatogenesis

abnormal epididymis morphology

abnormal cauda epididymis morphology

male infertility

Availability

Mouse Genotype

Rfx2^{Gt(IST10638H11)Tigm}/Rfx2^{Gt(IST10638H11)Tigm}

Rfx2^tm1.1Wrth/Rfx2^tm1.1Wrth

Rfx2^tm1.2Wrth/Rfx2^tm1.2Wrth

Rfx2^tm1Hncs/Rfx2^tm1Hncs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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