|
Symbol Name ID |
Ren1
renin 1 structural MGI:97898 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Proteinuria |
Focal segmental glomerulosclerosis |
Renal tubular atrophy |
Tubulointerstitial fibrosis |
Hyperechogenic kidneys |
Abnormal renal insterstitial morphology |
Renal hypoplasia |
Decreased glomerular filtration rate |
Nephritis |
Nephropathy |
Renal insufficiency |
Chronic kidney disease |
Impaired renal concentrating ability |
| Disease(s) Associated with REN | |||||||||||||
| familial juvenile hyperuricemic nephropathy |
| Mouse Phenotypes | renal/urinary system phenotype |
abnormal kidney afferent arteriole morphology |
abnormal kidney interlobular artery morphology |
abnormal urine homeostasis |
decreased urine osmolality |
albuminuria |
kidney inflammation |
abnormal kidney cortex morphology |
abnormal juxtaglomerular apparatus morphology |
abnormal juxtaglomerular cell morphology |
abnormal macula densa morphology |
abnormal renal glomerulus morphology |
glomerulosclerosis |
renal glomerulus atrophy |
renal glomerulus fibrosis |
renal glomerulus hypertrophy |
kidney cortex atrophy |
renal interstitial fibrosis |
abnormal kidney medulla morphology |
kidney papillary atrophy |
kidney papillary hypoplasia |
kidney medulla atrophy |
hydronephrosis |
decreased kidney weight |
small kidney |
kidney atrophy |
renal tubule atrophy |
proximal convoluted tubule brush border loss |
dilated renal tubule |
granular kidney |
decreased renal glomerular filtration rate |
polyuria |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||
| Ren1tm1.2Sig/Ren1tm1.2Sig | |||||||||||||||||||||||||||||||||
| Ren1tm1Afu/Ren1tm1Afu | |||||||||||||||||||||||||||||||||
| Ren1tm1Bjm/Ren1tm1Bjm | |||||||||||||||||||||||||||||||||
| Ren1tm1Gom/Ren1tm1Gom | |||||||||||||||||||||||||||||||||
| Ren1tm1Mgfs/Ren1tm1Mgfs | |||||||||||||||||||||||||||||||||
| Ren1tm1Tkh/Ren1tm1Tkh | |||||||||||||||||||||||||||||||||
| Ren1tm3Gom/Ren1tm3Gom | |||||||||||||||||||||||||||||||||
| Ren1tm3Gom/Ren1+ | |||||||||||||||||||||||||||||||||
| Tg(Alb1-Ren)1Unc/0 | |||||||||||||||||||||||||||||||||
| Tg(Alb1-Ren)2Unc/0 | |||||||||||||||||||||||||||||||||
| Ren1tm1.1Sig/Ren1tm1.1Sig Tg(GFAP-cre)25Mes/0 (conditional) |
* | ||||||||||||||||||||||||||||||||
| Ren1tm1.1Sig/Ren1tm1.1Sig Tg(Nes-cre)1Kln/0 (conditional) |
* | ||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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