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Symbol
Name
ID
Itgb1
integrin beta 1 (fibronectin receptor beta)
MGI:96610
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal glomerular capillary morphology
dilated glomerular capillary
increased mesangial cell number
increased kidney apoptosis
increased podocyte apoptosis
increased kidney cell proliferation
kidney medulla cyst
renal tubular acidosis
abnormal urine homeostasis
decreased urine osmolality
increased urine pH
increased urine protein level
albuminuria
abnormal kidney morphology
abnormal kidney collecting duct morphology
dilated kidney collecting duct
abnormal kidney cortex morphology
abnormal renal glomerular capsule morphology
podocyte foot process effacement
abnormal renal glomerulus basement membrane morphology
abnormal renal glomerulus morphology
expanded mesangial matrix
mesangiolysis
abnormal renal tubule epithelium morphology
abnormal kidney medulla morphology
kidney medulla hypoplasia
decreased kidney weight
small kidney
renal hypoplasia
dilated renal tubule
renal cast
absent kidney
pale kidney
single kidney
abnormal renal filtration rate
abnormal renal transport
isosthenuria
kidney failure
polyuria
Availability Mouse Genotype
Itgb1tm1Efu/Itgb1tm1Efu
Tg(ATP6V1B1-cre)45Rnel/0  (conditional)
Itgb1tm1Efu/Itgb1tm1Efu
Tg(NPHS2-cre)295Lbh/0  (conditional)
Itgb1tm1Ross/Itgb1tm1Ross
Tg(Hoxb7-cre)13Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory