Symbol
Name
ID

Fas
Fas cell surface death receptor
MGI:95484

Phenotype annotations related to renal/urinary system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Hypercalciuria

Hematuria

Pyuria

Proteinuria

Abnormality of the kidney

Glomerulonephritis

Lupus nephritis

Nephrolithiasis

Abnormal renal physiology

Nephritis

Renal insufficiency

Acute kidney injury

Chronic kidney disease

Renal cell carcinoma

Disease(s) Associated with FAS

autoimmune lymphoproliferative syndrome

cystic fibrosis

pre-eclampsia

renal cell carcinoma

systemic lupus erythematosus

Mouse Phenotypes

abnormal glomerular capillary endothelium morphology

abnormal glomerular capillary morphology

increased mesangial cell number

increased renal glomerulus apoptosis

increased kidney cell proliferation

increased urine protein level

albuminuria

kidney inflammation

glomerulonephritis

abnormal kidney morphology

podocyte foot process effacement

dilated renal glomerular capsule

abnormal renal glomerulus basement membrane morphology

increased renal glomerulus basement membrane thickness

abnormal renal glomerulus morphology

expanded mesangial matrix

cortical renal glomerulopathies

glomerular crescent

renal glomerular protein deposits

renal glomerular immunoglobulin deposits

renal glomerulus hypertrophy

renal cast

abnormal kidney physiology

kidney failure

Availability

Mouse Genotype

Fas^lpr/Fas^lpr

Fas^tm1Cgn/Fas^tm1Cgn
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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