Symbol Name ID |
Col4a5
collagen, type IV, alpha 5 MGI:88456 |
Darker colors indicate more annotations |
Human Phenotypes | Hematuria |
Microscopic hematuria |
Proteinuria |
Renal glomerular foam cells |
Glomerular basement membrane lamellation |
Thickened glomerular basement membrane |
Thin glomerular basement membrane |
Thickening of glomerular capillary wall |
Mesangial hypercellularity |
Glomerular C3 deposition |
IgA deposition in the glomerulus |
Focal segmental glomerulosclerosis |
Renal tubular atrophy |
Tubulointerstitial fibrosis |
Nephritis |
Nephrotic syndrome |
Renal insufficiency |
Stage 5 chronic kidney disease |
Disease(s) Associated with COL4A5 | ||||||||||||||||||
Alport syndrome | ||||||||||||||||||
X-linked Alport syndrome |
Mouse Phenotypes | abnormal glomerular capillary morphology |
dilated glomerular capillary |
increased mesangial cell number |
increased urine protein level |
albuminuria |
hematuria |
tubulointerstitial nephritis |
abnormal kidney morphology |
abnormal renal glomerular capsule morphology |
podocyte foot process effacement |
abnormal renal glomerulus basement membrane morphology |
increased renal glomerulus basement membrane thickness |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
glomerulosclerosis |
renal glomerular synechia |
renal interstitial fibrosis |
renal tubule atrophy |
abnormal renal tubule morphology |
dilated renal tubule |
pale kidney |
|
Availability | Mouse Genotype | |||||||||||||||||||||
Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi | ||||||||||||||||||||||
Col4a5tm1Yseg/Col4a5+ | ||||||||||||||||||||||
Col4a5em1Keha/Y | ||||||||||||||||||||||
Col4a5tm1b(EUCOMM)Wtsi/Y | ||||||||||||||||||||||
Col4a5tm1Yseg/Y |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/28/2024 MGI 6.13 |
|
|