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Symbol
Name
ID
Flcn
folliculin
MGI:2442184
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations
Human Phenotypes
Renal cyst
Renal neoplasm
Renal cell carcinoma
Disease(s) Associated with FLCN
Birt-Hogg-Dube syndrome
colorectal cancer
renal cell carcinoma

Mouse Phenotypes
abnormal kidney vasculature morphology
kidney hemorrhage
increased kidney cell proliferation
kidney cyst
polycystic kidney
enlarged kidney
increased kidney weight
increased renal carcinoma incidence
increased kidney tumor incidence
abnormal kidney collecting duct morphology
dilated kidney collecting duct
renal glomerulus atrophy
abnormal kidney corticomedullary boundary morphology
abnormal renal tubule epithelium morphology
abnormal kidney pyramid morphology
abnormal renal tubule morphology
dilated proximal convoluted tubule
dilated renal tubule
kidney failure
Availability Mouse Genotype
FlcnGt(RRX115)Byg/Flcn+
Flcntm1Btt/Flcntm1Btt
Tg(Cdh16-cre)91Igr/0  (conditional)
Flcntm1Baba/Flcntm1.1Lss
Tg(Cdh16-cre)91Igr/0  (conditional)
Flcntm1Baba/Flcntm1.1Lss
Tg(CAG-cre/Esr1*)1Lbe/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory