Symbol
Name
ID

Fras1
Fraser extracellular matrix complex subunit 1
MGI:2385368

Phenotype annotations related to renal/urinary system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypospadias	Renal hypoplasia/aplasia	Renal hypoplasia
Disease(s) Associated with FRAS1
Fraser syndrome 1

Mouse Phenotypes

renal/urinary system phenotype

abnormal glomerular capillary morphology

increased metanephric mesenchyme apoptosis

kidney cyst

abnormal glomerular capsule space morphology

abnormal renal glomerulus morphology

abnormal glomerular mesangium morphology

cortical renal glomerulopathies

glomerulosclerosis

abnormal kidney development

abnormal metanephric mesenchyme morphology

abnormal metanephros morphology

delayed kidney development

small kidney

absent kidney

single kidney

abnormal ureteric bud morphology

impaired branching involved in ureteric bud morphogenesis

Availability

Mouse Genotype

Fras1^b2b3323Clo/Fras1^b2b3323Clo

Fras1^bfb/Fras1^bfb

Fras1^bl/Fras1^bl

Fras1^rdf/Fras1^rdf

Fras1^tm1.2Pjsc/Fras1^tm1.2Pjsc

Fras1^tm1Chpk/Fras1^tm1Chpk

Fras1^bl/Fras1^tm1.2Pjsc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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