Symbol
Name
ID

Tcf21
transcription factor 21
MGI:1202715

Phenotype annotations related to renal/urinary system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal glomerular capillary morphology

abnormal peritubular capillary morphology

abnormal kidney vasculature morphology

enlarged kidney

abnormal urine homeostasis

increased urine protein level

abnormal kidney morphology

abnormal renal glomerular capsule morphology

abnormal podocyte morphology

abnormal podocyte foot process morphology

podocyte foot process effacement

abnormal renal glomerulus morphology

glomerulosclerosis

decreased renal glomerulus number

renal glomerulus atrophy

abnormal kidney development

abnormal kidney mesenchyme morphology

delayed kidney development

abnormal kidney medulla morphology

small kidney

kidney atrophy

renal hypoplasia

decreased nephron number

abnormal proximal convoluted tubule morphology

absent proximal convoluted tubule brush border

pale kidney

abnormal ureteric bud morphology

abnormal branching involved in ureteric bud morphogenesis

impaired branching involved in ureteric bud morphogenesis

abnormal ureteric bud tip morphology

abnormal kidney physiology

Availability

Mouse Genotype

Tcf21^tm1Eno/Tcf21^tm1Eno

Tcf21^tm1Jrt/Tcf21^tm1Jrt

Tcf21^tm2Eno/Tcf21^tm2Eno

Tcf21^em1(IMPC)Mbp/Tcf21⁺

Tcf21^tm2.1Seq/Tcf21^tm1Jrt
Tg(Nphs2-cre)1Seq/0 (conditional)

Tcf21^tm2.1Seq/Tcf21^tm1Jrt
Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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