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Symbol Name ID |
Fat1
FAT atypical cadherin 1 MGI:109168 |
| Darker colors indicate more annotations |
| Human Phenotypes | Renal cell carcinoma |
| Disease(s) Associated with FAT1 | |
| colorectal cancer |
| Mouse Phenotypes | kidney cyst |
increased urine protein level |
albuminuria |
abnormal podocyte morphology |
fused podocyte foot processes |
podocyte foot process effacement |
abnormal podocyte slit junction morphology |
abnormal podocyte slit diaphragm morphology |
podocyte microvillus transformation |
abnormal glomerular mesangium morphology |
glomerulosclerosis |
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| Availability | Mouse Genotype | |||||||||||
| Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 |
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| Fat1tm1Cfc/Fat1tm1Cfc | ||||||||||||
| Fat1tm1.1Nsib/Fat1tm1.1Nsib Tg(NPHS2-cre)295Lbh/0 (conditional) |
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| Fat1tm1.1Nsib/Fat1+ Tg(NPHS2-cre)295Lbh/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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