Symbol
Name
ID

Gpc3
glypican 3
MGI:104903

Phenotype annotations related to renal/urinary system

Darker colors indicate more annotations

Human Phenotypes	Hypospadias	Hydronephrosis	Duplication of renal pelvis	Enlarged kidney	Renal cyst	Multicystic kidney dysplasia	Nephroblastoma	Hydroureter	Ureteral duplication
Disease(s) Associated with GPC3	Hypospadias	Hydronephrosis	Duplication of renal pelvis	Enlarged kidney	Renal cyst	Multicystic kidney dysplasia	Nephroblastoma	Hydroureter	Ureteral duplication
nephroblastoma
Simpson-Golabi-Behmel syndrome type 1

Mouse Phenotypes

kidney cyst

kidney cortex cyst

kidney corticomedullary cyst

kidney medulla cyst

enlarged kidney

abnormal kidney morphology

abnormal kidney collecting duct morphology

abnormal kidney cortex morphology

kidney cortex atrophy

abnormal kidney development

abnormal kidney medulla morphology

hydronephrosis

abnormal kidney weight

dilated renal tubule

abnormal ureteric bud morphology

abnormal branching involved in ureteric bud morphogenesis

impaired branching involved in ureteric bud morphogenesis

Availability

Mouse Genotype

Gpc3^Gt(Ex136)Byg/Gpc3^Gt(Ex136)Byg

Gpc3^tm1Fil/Gpc3^tm1Fil

Gpc3^Gt(Ex136)Byg/Gpc3⁺

Gpc3^tm1Fil/Gpc3⁺

Gpc3^tm1Snd/Gpc3⁺

Gpc3^Gt(Ex136)Byg/Y

Gpc3^tm1Arge/Y

Gpc3^tm1Fil/Y

Gpc3^tm1Snd/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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