|
Symbol Name ID |
Col4a3
collagen, type IV, alpha 3 MGI:104688 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hematuria |
Microscopic hematuria |
Proteinuria |
Renal glomerular foam cells |
Glomerular basement membrane lamellation |
Thickened glomerular basement membrane |
Thin glomerular basement membrane |
Thickening of glomerular capillary wall |
Mesangial hypercellularity |
Glomerular C3 deposition |
IgA deposition in the glomerulus |
Focal segmental glomerulosclerosis |
Glomerulonephritis |
Renal tubular atrophy |
Tubulointerstitial fibrosis |
Nephrocalcinosis |
Nephritis |
Nephrotic syndrome |
Renal insufficiency |
Stage 5 chronic kidney disease |
| Disease(s) Associated with COL4A3 | ||||||||||||||||||||
| Alport syndrome | ||||||||||||||||||||
| autosomal dominant Alport syndrome | ||||||||||||||||||||
| autosomal recessive Alport syndrome | ||||||||||||||||||||
| benign familial hematuria |
| Mouse Phenotypes | abnormal glomerular capillary morphology |
glomerulus hemorrhage |
increased mesangial cell number |
increased kidney weight |
increased urine protein level |
albuminuria |
hematuria |
glomerulonephritis |
abnormal kidney morphology |
abnormal podocyte morphology |
abnormal podocyte foot process morphology |
podocyte foot process effacement |
podocyte microvillus transformation |
abnormal renal glomerulus basement membrane morphology |
abnormal renal glomerulus basement membrane thickness |
increased renal glomerulus basement membrane thickness |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
glomerulosclerosis |
glomerular crescent |
renal glomerulus fibrosis |
renal interstitial fibrosis |
small kidney |
kidney atrophy |
renal tubule atrophy |
renal cast |
granular kidney |
pale kidney |
decreased renal glomerular filtration rate |
kidney failure |
polyuria |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Col4a3tm1b(EUCOMM)Wtsi/Col4a3tm1b(EUCOMM)Wtsi | ||||||||||||||||||||||||||||||||
| Col4a3tm1Dec/Col4a3tm1Dec | ||||||||||||||||||||||||||||||||
| Col4a3tm1Jhm/Col4a3tm1Jhm | ||||||||||||||||||||||||||||||||
| Col4a3tm1.1Rkl/Col4a3+ | ||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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