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Symbol Name ID |
Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7 MGI:99779 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | EEG abnormality |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Social and occupational deterioration |
| Disease(s) Associated with CHRNA7 | ||||||
| schizophrenia |
| Mouse Phenotypes | nervous system phenotype |
abnormal seizure response to pharmacological agent |
increased neuron apoptosis |
abnormal brain morphology |
abnormal brain interneuron morphology |
abnormal cerebral cortex morphology |
abnormal cerebral cortex pyramidal cell morphology |
abnormal somatosensory cortex morphology |
decreased CNS synapse formation |
abnormal GABAergic neuron morphology |
failure of neuromuscular synapse presynaptic differentiation |
abnormal GABAergic neuron physiology |
abnormal GABA-mediated receptor currents |
abnormal nicotine-mediated receptor currents |
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| Availability | Mouse Genotype | ||||||||||||||
| Chrna7tm1Bay/Chrna7tm1Bay | * | ||||||||||||||
| Chrna7tm2Bay/Chrna7tm2Bay | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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