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Symbol
Name
ID

Ryr2
ryanodine receptor 2, cardiac
MGI:99685

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Seizure
Disease(s) Associated with RYR2	Seizure
catecholaminergic polymorphic ventricular tachycardia 1

Mouse Phenotypes		nervous system phenotype	increased susceptibility to pharmacologically induced seizures	tonic-clonic seizures	abnormal nervous system electrophysiology	abnormal action potential	abnormal afterhyperpolarization	abnormal brain wave pattern	abnormal miniature excitatory postsynaptic currents	decreased paired-pulse ratio
Availability	Mouse Genotype	nervous system phenotype		tonic-clonic seizures	abnormal nervous system electrophysiology	abnormal action potential	abnormal afterhyperpolarization	abnormal brain wave pattern	abnormal miniature excitatory postsynaptic currents	decreased paired-pulse ratio
	Ryr2^tm1.1Hnis/Ryr2^tm1.1Hnis	*
	Ryr2^tm2Amks/Ryr2^tm2Amks
	Ryr2^em1Swch/Ryr2⁺
	Ryr2^tm1Slh/Ryr2⁺
	Ryr2^tm2Amks/Ryr2⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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