|
Symbol Name ID |
Fgf8
fibroblast growth factor 8 MGI:99604 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Anosmia |
Hyposmia |
Small pituitary gland |
| Disease(s) Associated with FGF8 | |||
| hypogonadotropic hypogonadism 6 with or without anosmia |
| Mouse Phenotypes | nervous system phenotype |
decreased neuron apoptosis |
increased neuron apoptosis |
abnormal neural tube morphology |
abnormal neural crest cell morphology |
open neural tube |
abnormal rhombomere morphology |
abnormal pituitary gland morphology |
abnormal forebrain development |
small embryonic telencephalon |
abnormal Raphe nucleus morphology |
abnormal midbrain morphology |
absent inferior colliculus |
abnormal substantia nigra morphology |
abnormal hypothalamus morphology |
absent olfactory bulb |
absent cerebellum |
small cerebellum |
decreased dopaminergic neuron number |
abnormal serotonergic neuron morphology |
abnormal trigeminal nerve morphology |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Fgf8tm1.1Jyhl/Fgf8tm1.1Jyhl | ||||||||||||||||||||||
| Fgf8tm1.1Mrt/Fgf8tm1.1Mrt | ||||||||||||||||||||||
| Fgf8tm2.1Jyhl/Fgf8tm2.1Jyhl | * | |||||||||||||||||||||
| Fgf8tm1.1Mrt/Fgf8tm1.2Mrt | ||||||||||||||||||||||
| Fgf8tm1.1Mrt/Fgf8tm1.4Mrt | ||||||||||||||||||||||
| Fgf8tm2Mrt/Fgf8+ | ||||||||||||||||||||||
| En1tm7(cre/ESR1)Alj/0 Fgf8tm1.1Jyhl/Fgf8tm1.3Mrt (conditional) |
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| Fgf8tm1.1Mrt/Fgf8tm1.4Mrt Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| Fgf8tm1.2Mrt/Fgf8tm1.3Mrt Tg(Nes-cre)1Atp/0 (conditional) |
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| Fgf8tm1.2Mrt/Fgf8tm1.3Mrt Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| Fgf8tm1.3Mrt/Fgf8tm1.4Mrt Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| En1tm7(cre/ESR1)Alj/0 Fgf8tm1.3Mrt/Fgf8tm1.4Mrt (conditional) |
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| Fgf8tm1.3Mrt/Fgf8tm2Mrt Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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