Symbol
Name
ID

Wnt1
wingless-type MMTV integration site family, member 1
MGI:98953

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Hypoplasia of the pons	Schizencephaly	Cerebellar hypoplasia	Global developmental delay
Disease(s) Associated with WNT1
osteogenesis imperfecta type 15

Mouse Phenotypes

decreased rhombomere 1 size

abnormal hindbrain development

abnormal cerebellum development

abnormal midbrain development

abnormal cranial flexure morphology

abnormal midbrain-hindbrain boundary development

absent midbrain-hindbrain boundary

hydrocephaly

decreased midbrain size

abnormal brain white matter morphology

abnormal midbrain morphology

abnormal inferior colliculus morphology

absent midbrain

abnormal forebrain morphology

abnormal frontal lobe morphology

abnormal metencephalon morphology

abnormal cerebellar cortex morphology

abnormal cerebellum anterior vermis morphology

absent cerebellum

absent metencephalon

Availability

Mouse Genotype

Wnt1^sw/Wnt1^sw

Wnt1^tm1Amc/Wnt1^tm1Amc

Wnt1^tm1Brd/Wnt1^tm1Brd

Wnt1^tm1Mrc/Wnt1^tm1Mrc

Wnt1^tm1.1Mze/Wnt1^tm1.1Mze
En1^tm2(cre)Wrst/En1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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