Symbol
Name
ID

Vldlr
very low density lipoprotein receptor
MGI:98935

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Hypoplasia of the brainstem

Pachygyria

Simplified gyral pattern

Cerebral cortical atrophy

Hypoplasia of the corpus callosum

Corpus callosum atrophy

Aplasia of the inferior half of the cerebellar vermis

Inferior cerebellar vermis hypoplasia

Atrophy of the dentate nucleus

Cerebellar hypoplasia

Cerebellar atrophy

Global brain atrophy

Ataxia

Cerebellar ataxia associated with quadrupedal gait

Dysdiadochokinesis

Dysmetria

Gait ataxia

Truncal ataxia

Slurred speech

Tremor

Intention tremor

Delayed speech and language development

Dysarthria

Poor speech

Intellectual disability

Intellectual disability, mild

Intellectual disability, progressive

Intellectual disability, severe

Hyperreflexia

Lower limb hyperreflexia

Hyporeflexia

Broad-based gait

Inability to walk

Global developmental delay

Delayed ability to walk

Seizure

Disease(s) Associated with VLDLR

cerebellar ataxia, mental retardation and dysequlibrium syndrome

Mouse Phenotypes

abnormal brain morphology

abnormal brain development

reduced cerebellar foliation

abnormal cerebellum morphology

small cerebellum

decreased retina photoreceptor cell number

abnormal retina photoreceptor morphology

retina photoreceptor degeneration

impaired synaptic plasticity

abnormal long-term potentiation

reduced long-term potentiation

Availability

Mouse Genotype

Vldlr^m1Btlr/Vldlr^m1Btlr

Vldlr^tm1Her/Vldlr^tm1Her

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23