|
Symbol Name ID |
Ntrk1
neurotrophic tyrosine kinase, receptor, type 1 MGI:97383 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Orthostatic hypotension due to autonomic dysfunction |
Postural hypotension with compensatory tachycardia |
Dysphagia |
Painless fractures due to injury |
Difficulty walking |
Decreased number of small peripheral myelinated nerve fibers |
EEG abnormality |
Abnormality of peripheral nerve conduction |
Abnormal emotion |
Emotional lability |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Nail-biting |
Hyperactivity |
Impulsivity |
Self-mutilation |
Social and occupational deterioration |
Short attention span |
Intellectual disability |
Global developmental delay |
Specific learning disability |
Somatic sensory dysfunction |
Pain insensitivity |
Trophic limb changes |
Hyperesthesia |
Impaired temperature sensation |
Distal sensory impairment |
Abnormality of the autonomic nervous system |
Abnormal autonomic nervous system physiology |
| Disease(s) Associated with NTRK1 | |||||||||||||||||||||||||||||||
| hereditary sensory neuropathy type 4 | |||||||||||||||||||||||||||||||
| schizophrenia |
| Mouse Phenotypes | nervous system phenotype |
increased neuron apoptosis |
abnormal axon extension |
abnormal sympathetic ganglion morphology |
small superior cervical ganglion |
abnormal innervation |
abnormal sensory neuron innervation pattern |
abnormal cholinergic neuron morphology |
abnormal neurite morphology |
decreased sensory neuron number |
small trigeminal ganglion |
small dorsal root ganglion |
abnormal sympathetic nervous system physiology |
abnormal neuron physiology |
abnormal sensory neuron physiology |
|
| Availability | Mouse Genotype | |||||||||||||||
| Ntrk1em1Krvl/Ntrk1em1Krvl | * | |||||||||||||||
| Ntrk1tm1.1Azmo/Ntrk1tm1.1Azmo | * | |||||||||||||||
| Ntrk1tm1.1Jcar/Ntrk1tm1.1Jcar | ||||||||||||||||
| Ntrk1tm1Apat/Ntrk1tm1Apat | ||||||||||||||||
| Ntrk1tm1Bbd/Ntrk1tm1Bbd | ||||||||||||||||
| Ntrk1tm1Par/Ntrk1tm1Par | ||||||||||||||||
| Ntrk1tm2.1Tes/Ntrk1tm2.1Tes | * | |||||||||||||||
| Ntrk1tm2.1Lfr/Ntrk1tm2.1Lfr Tg(dlx5a-cre)1Mekk/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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