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Symbol
Name
ID
Nedd4
neural precursor cell expressed, developmentally down-regulated 4
MGI:97297
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
nervous system phenotype
increased embryonic neuroepithelium apoptosis
decreased cranial neural crest cell number
abnormal cerebral hemisphere morphology
thin cerebral cortex
abnormal neuron morphology
abnormal dendrite morphology
abnormal synapse morphology
abnormal synaptic vesicle number
abnormal cranial ganglia morphology
abnormal glossopharyngeal ganglion morphology
small trigeminal ganglion
abnormal vagus ganglion morphology
decreased excitatory postsynaptic current amplitude
abnormal miniature excitatory postsynaptic currents
Availability Mouse Genotype
Nedd4Gt(XA209)Byg/Nedd4Gt(XA209)Byg
Nedd4tm2Bros/Nedd4tm2Bros *
Nedd4tm3.1Bros/Nedd4tm3.1Bros
Neurod6tm1(cre)Kan/Neurod6+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory