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Symbol
Name
ID
Itgb1
integrin beta 1 (fibronectin receptor beta)
MGI:96610
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
nervous system phenotype
abnormal radial glial cell morphology
radial glial endfoot detachment
abnormal neuronal migration
abnormal neuronal precursor cell migration
abnormal neural tube morphology
increased embryonic neuroepithelium thickness
abnormal enteric neural crest cell morphology
open neural tube
spina bifida
kinked neural tube
wavy neural tube
abnormal nervous system morphology
abnormal enteric neuron morphology
abnormal brain morphology
abnormal cortical marginal zone morphology
abnormal Cajal-Retzius cell morphology
abnormal cerebellum development
abnormal cerebellar foliation
abnormal rostral migratory stream morphology
decreased hindbrain size
abnormal choroid plexus morphology
abnormal cerebral cortex morphology
small olfactory bulb
abnormal cerebellum morphology
abnormal cerebellum vermis morphology
small cerebellum
abnormal CNS glial cell morphology
absent Schwann cell precursors
abnormal innervation
abnormal innervation pattern to muscle
abnormal meninges morphology
abnormal neuromuscular synapse morphology
abnormal cranial nerve morphology
abnormal sciatic nerve morphology
abnormal myelination
Availability Mouse Genotype
Itgb1tm2Son/Itgb1tm2Son !
Itgb1tm1Mll/Itgb1tm1Mll
Tg(Nes-cre)1Kln/0  (conditional)
Itgb1tm1Mll/Itgb1tm1Mll
Emx1tm1(cre)Krj/Emx1+  (conditional)
*
Itgb1tm1Mll/Itgb1tm1Mll
Wnt3atm1(cre)Eag/Wnt3a+  (conditional)
*
Itgb1tm1Lscd/Itgb1tm1Mll
Tg(Nes-cre)1Kln/0  (conditional)
Itgb1tm1Lscd/Itgb1tm1Ref
Tg(PLAT-cre)116Sdu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory