Symbol Name ID |
Igf1r
insulin-like growth factor I receptor MGI:96433 |
Darker colors indicate more annotations |
Human Phenotypes | Anorexia |
Horner syndrome |
Lewy bodies |
Spinal cord compression |
Neuroblastoma |
Neoplasm of the nervous system |
Ataxia |
Parkinsonism |
Myoclonus |
Irritability |
Delusion |
Visual hallucination |
Dementia |
Fluctuations in consciousness |
Antalgic gait |
Disease(s) Associated with IGF1R | |||||||||||||||
Lewy body dementia | |||||||||||||||
neuroblastoma | |||||||||||||||
pancreatic cancer |
Mouse Phenotypes | abnormal inner hair cell kinocilium morphology |
decreased oligodendrocyte progenitor number |
abnormal cochlear hair cell development |
decreased cochlear hair cell number |
decreased cochlear inner hair cell number |
decreased cochlear outer hair cell number |
abnormal cochlear hair cell stereociliary bundle morphology |
abnormal cochlear inner hair cell morphology |
abnormal cochlear outer hair cell morphology |
decreased brain size |
abnormal brainstem morphology |
abnormal CNS glial cell morphology |
abnormal oligodendrocyte morphology |
abnormal spinal cord morphology |
abnormal myelination |
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Availability | Mouse Genotype | |||||||||||||||
Igf1rtm1Arge/Igf1rtm1Arge | ||||||||||||||||
Igf1rtm2.1Arge/Igf1rtm2.1Arge | ||||||||||||||||
Igf1rtm1Jcbr/Igf1rtm1Jcbr Tg(Fabp4-cre)1Abel/? (conditional) |
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Igf1rtm1Arge/Igf1rtm2Arge Tg(Camk2a-cre)2Szi/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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