Symbol Name ID |
Igf1
insulin-like growth factor 1 MGI:96432 |
Darker colors indicate more annotations |
Human Phenotypes | Anorexia |
Abnormality of the nervous system |
Gliosis |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Gait ataxia |
Bradykinesia |
Chorea |
Depression |
Personality changes |
Polydipsia |
Polyphagia |
Dementia |
Hyperreflexia |
Seizure |
Disease(s) Associated with IGF1 | |||||||||||||||
Huntington's disease | |||||||||||||||
myopia | |||||||||||||||
pancreatic cancer | |||||||||||||||
type 1 diabetes mellitus |
Mouse Phenotypes | increased neuron apoptosis |
abnormal brain morphology |
abnormal olfactory bulb layer morphology |
abnormal olfactory bulb external plexiform layer morphology |
abnormal olfactory bulb mitral cell layer morphology |
abnormal mitral cell morphology |
abnormal sensory neuron innervation pattern |
decreased motor neuron number |
abnormal cochlear ganglion morphology |
cochlear ganglion degeneration |
small cochlear ganglion |
abnormal cochlear nerve morphology |
abnormal nervous system physiology |
abnormal myelination |
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Availability | Mouse Genotype | ||||||||||||||
Igf1tm1Arge/Igf1tm1Arge | |||||||||||||||
Igf1tm1Ts/Igf1tm1Ts | |||||||||||||||
Igf1tm1Arge/Igf1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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