|
Symbol Name ID |
Hras
Harvey rat sarcoma virus oncogene MGI:96224 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Dandy-Walker malformation |
Vestibular schwannoma |
Cerebral calcification |
Hydrocephalus |
Ventriculomegaly |
Aplasia/Hypoplasia of the corpus callosum |
Cerebral atrophy |
Hemimegalencephaly |
Porencephalic cyst |
Aplasia/Hypoplasia of the cerebellum |
Chiari type I malformation |
Enlarged cerebellum |
EEG abnormality |
Abnormal nonverbal communicative behavior |
Delayed speech and language development |
Lack of spontaneous play |
Impaired ability to form peer relationships |
Autism |
Inflexible adherence to routines |
Motor stereotypy |
Restrictive behavior |
Intellectual disability |
Obstructive sleep apnea |
Hyperreflexia |
Reduced tendon reflexes |
Global developmental delay |
Seizure |
| Disease(s) Associated with HRAS | |||||||||||||||||||||||||||
| autistic disorder | |||||||||||||||||||||||||||
| Costello syndrome | |||||||||||||||||||||||||||
| large congenital melanocytic nevus | |||||||||||||||||||||||||||
| linear nevus sebaceous syndrome |
| Mouse Phenotypes | nervous system phenotype |
increased astrocytoma incidence |
hydrocephaly |
abnormal astrocyte morphology |
|
| Availability | Mouse Genotype | ||||
| Hrastm1Grnt/Hrastm1Grnt | * | ||||
| Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu | |||||
| Tg(GFAP-Hras1)2Agu/0 | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/21/2024 MGI 6.23 |
|
|
|
||
Analysis Tools