Symbol
Name
ID

Gata3
GATA binding protein 3
MGI:95663

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Hypocalcemic seizures	Cerebral calcification	Basal ganglia calcification	Seizure
Disease(s) Associated with GATA3	Hypocalcemic seizures	Cerebral calcification	Basal ganglia calcification	Seizure
hypoparathyroidism
hypoparathyroidism-deafness-renal disease syndrome

Mouse Phenotypes

abnormal axon guidance

abnormal neural tube morphology

abnormal cochlear hair cell morphology

decreased cochlear hair cell number

absent cochlear hair cells

cochlear inner hair cell degeneration

abnormal cochlear outer hair cell morphology

cochlear outer hair cell degeneration

cochlear hair cell degeneration

abnormal sympathetic ganglion morphology

small superior cervical ganglion

abnormal sympathetic neuron innervation pattern

abnormal brain morphology

abnormal Raphe nucleus morphology

abnormal sensory neuron innervation pattern

abnormal nervous system development

abnormal cochlear ganglion morphology

cochlear ganglion degeneration

small trigeminal ganglion

abnormal vestibular ganglion morphology

abnormal facial nerve morphology

Availability

Mouse Genotype

Gata3^tm1Gsv/Gata3^tm1Gsv

Gata3^tm1Jeng/Gata3^tm1Jeng

Gata3^tm2Gsv/Gata3^tm2Gsv

Gata3^tm1Gsv/Gata3⁺

Gata3^tm2Gsv/Gata3⁺

Gata3^tm1.1Gan/Gata3^tm1.1Gan
Tg(Pax2-cre)1Akg/0 (conditional)

Gata3^tm1Jfz/Gata3^tm1Jfz
Tg(Fev-cre)1Esd/0 (conditional)

Bhlhe22^{tm3.1(cre)Meg}/Bhlhe22⁺
Gata3^tm1Jfz/Gata3^tm1Jfz (conditional)

Gata3^tm3Gsv/Gata3^tm3Gsv
Tg(Dbh-icre)1Gsc/0 (conditional)

Gata3^tm3Gsv/Gata3^tm3Gsv
Tg(Dbh-cre/ERT2)198.1Hroh/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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