Symbol Name ID |
Gad1
glutamate decarboxylase 1 MGI:95632 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Spasticity |
Hypoplasia of the corpus callosum |
Cerebral atrophy |
Cerebellar atrophy |
Tetraparesis |
EEG abnormality |
EEG with burst suppression |
Hypsarrhythmia |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Addictive alcohol use |
Social and occupational deterioration |
Intellectual disability, profound |
Hyperreflexia |
Dystonia |
Hyperkinetic movements |
Global developmental delay |
Bilateral tonic-clonic seizure with generalized onset |
Epileptic spasm |
Myoclonic seizure |
Disease(s) Associated with GAD1 | ||||||||||||||||||||||
alcohol dependence | ||||||||||||||||||||||
developmental and epileptic encephalopathy 89 | ||||||||||||||||||||||
schizophrenia |
Mouse Phenotypes | nervous system phenotype |
abnormal nervous system morphology |
abnormal brain interneuron morphology |
abnormal visual cortex morphology |
abnormal nervous system electrophysiology |
abnormal GABA-mediated receptor currents |
abnormal inhibitory postsynaptic currents |
decreased prepulse inhibition |
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Availability | Mouse Genotype | ||||||||
Gad1tm1Tama/Gad1tm1Tama | |||||||||
Gad1tm1.1Rpa/Gad1+ | |||||||||
Gad1tm1.1Tama/Gad1+ | * | ||||||||
Tg(Pvalb-tdTomato/RNAi:Gad1)3Mirn/? | |||||||||
Gad1tm1Rpa/Gad1tm1Rpa (conditional) | |||||||||
Gad1tm2Oba/Gad1tm2Oba Ptf1atm1.1(cre)Cvw/Ptf1a+ (conditional) |
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Gad1tm1Rpa/Gad1+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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