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Symbol
Name
ID

Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
MGI:95614

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Spasticity

CNS hypomyelination

Cerebral palsy

Chorea

EEG abnormality

Abnormal nonverbal communicative behavior

Reduced eye contact

Delayed speech and language development

Lack of spontaneous play

Impaired ability to form peer relationships

Autistic behavior

Autism

Addictive alcohol use

Inflexible adherence to routines

Motor stereotypy

Restrictive behavior

Intellectual disability

Inability to walk

Global developmental delay

Severe global developmental delay

Seizure

Status epilepticus

Disease(s) Associated with GABRA2

alcohol dependence

autistic disorder

developmental and epileptic encephalopathy 78

Mouse Phenotypes		abnormal CNS synaptic transmission	abnormal GABA-mediated receptor currents	abnormal miniature inhibitory postsynaptic currents
Availability	Mouse Genotype	abnormal CNS synaptic transmission	abnormal GABA-mediated receptor currents	abnormal miniature inhibitory postsynaptic currents
	Gabra2^tm1.1Geh/Gabra2^tm1.1Geh
	Gabra2^tm1.1Uru/Gabra2^tm1.1Uru
	Gabra2^tm2.1Uru/Gabra2^tm2.1Uru Tg(Scn10a-cre)1Rkun/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23