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Symbol
Name
ID
Fshr
follicle stimulating hormone receptor
MGI:95583
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Increased circulating gonadotropin level
Ataxia
Disease(s) Associated with FSHR
46 XX gonadal dysgenesis
ovarian dysgenesis 1

Mouse Phenotypes
increased gonadotroph cell number
increased thyrotroph cell number
adenohypophysis hyperplasia
increased pituitary gland weight
pituitary gland hyperplasia
increased prolactinoma incidence
abnormal dentate gyrus morphology
hippocampal neuron degeneration
astrocytosis
neurodegeneration
Availability Mouse Genotype
Fshrtm1Saco/Fshrtm1Saco
Fshrtm1Saco/Fshr+
Tg(AMH-Fshr*D580H)#Hht/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory