About   Help   FAQ
Symbol
Name
ID 		Flna
filamin, alpha
MGI:95556
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Cerebral hemorrhage
Microcephaly
Progressive microcephaly
Encephalocele
Stroke
Ectopic posterior pituitary
Optic nerve hypoplasia
Spastic diplegia
Abnormal nervous system morphology
Hydrocephalus
Thin corpus callosum
Partial agenesis of the corpus callosum
Hypoplasia of the corpus callosum
Cerebellar hypoplasia
Chiari type I malformation
Myelomeningocele
Spina bifida
Abnormality of neuronal migration
Gray matter heterotopia
Periventricular heterotopia
Periventricular nodular heterotopia
Tetraparesis
Hypsarrhythmia
Increased intracranial pressure
Reduced eye contact
Delayed speech and language development
Autism
Diminished ability to concentrate
Intellectual disability
Intellectual disability, mild
Intellectual disability, severe
Obstructive sleep apnea
Gait disturbance
Headache
Global developmental delay
Mild global developmental delay
Motor delay
Seizure
Focal-onset seizure
Focal motor seizure
Infantile spasms
Disease(s) Associated with FLNA
craniosynostosis
frontometaphyseal dysplasia 1
Melnick-Needles syndrome
otopalatodigital syndrome type 1
otopalatodigital syndrome type 2
periventricular nodular heterotopia
X-linked cardiac valvular dysplasia
X-linked chronic idiopathic intestinal pseudo-obstruction

Mouse Phenotypes
abnormal brain size
Availability Mouse Genotype
Flnatm1.1Caw/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory