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Symbol
Name
ID
Egfr
epidermal growth factor receptor
MGI:95294
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Anorexia
Disease(s) Associated with EGFR
pancreatic cancer

Mouse Phenotypes
nervous system phenotype
abnormal gonadotroph morphology
decreased lactotroph cell number
decreased somatotroph cell number
small adenohypophysis
abnormal cerebellum external granule cell layer morphology
decreased brain size
abnormal cerebral cortex morphology
thin cerebral cortex
abnormal olfactory bulb morphology
decreased Purkinje cell number
small cerebellum
abnormal sensory neuron innervation pattern
abnormal dorsal root ganglion morphology
Availability Mouse Genotype
Egfrtm1.1Dwt/Egfrtm1.1Dwt
Egfrtm1Mag/Egfrtm1Mag
Tg(Gh1-rtTA)4-3Jek/0
Tg(tetO-Egfr*)2-9Jek/0
Egfrtm1Dwt/Egfrtm1Dwt
Tg(KRT14-cre)1Amc/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory