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Symbol Name ID |
Chrm1
cholinergic receptor, muscarinic 1, CNS MGI:88396 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Facial palsy |
Dysphagia |
Fatigable weakness |
Dysarthria |
| Disease(s) Associated with CHRM1 | ||||
| myasthenia gravis |
| Mouse Phenotypes | nervous system phenotype |
abnormal auditory cortex morphology |
abnormal auditory cortex tonotopy |
abnormal CNS synapse formation |
abnormal nervous system electrophysiology |
abnormal excitatory postsynaptic currents |
abnormal excitatory postsynaptic potential |
abnormal inhibitory postsynaptic currents |
abnormal miniature excitatory postsynaptic currents |
abnormal long-term depression |
reduced long-term depression |
decreased paired-pulse facilitation |
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| Availability | Mouse Genotype | ||||||||||||
| Chrm1tm1Jwe/Chrm1tm1Jwe | * | ||||||||||||
| Chrm1tm1Kano/Chrm1tm1Kano | |||||||||||||
| Chrm1tm1Nmn/Chrm1tm1Nmn | |||||||||||||
| Chrm1tm1Stl/Chrm1tm1Stl | |||||||||||||
| Chrm1tm2.1Stl/Chrm1tm2.1Stl Emx1tm1.1(cre)Ito/0 (conditional) |
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| Chrm1tm2.1Stl/Chrm1tm2.1Stl Tg(Grik4-cre)G32-4Stl/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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