Symbol Name ID |
Cdh2
cadherin 2 MGI:88355 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Agenesis of corpus callosum |
Interhypothalamic adhesion |
Interhemispheric cyst |
Periventricular heterotopia |
Anxiety |
Auditory hallucination |
Autistic behavior |
Attention deficit hyperactivity disorder |
Impulsivity |
Self-injurious behavior |
Intellectual disability |
Bimanual synkinesia |
Global developmental delay |
Delayed fine motor development |
Delayed gross motor development |
Focal impaired awareness seizure |
Infantile spasms |
Disease(s) Associated with CDH2 | |||||||||||||||||
agenesis of corpus callosum, cardiac, ocular, and genital syndrome |
Mouse Phenotypes | nervous system phenotype |
abnormal radial glial cell morphology |
abnormal neuronal migration |
wavy neural tube |
abnormal brain development |
abnormal cortical ventricular zone morphology |
abnormal hippocampus pyramidal cell morphology |
abnormal cerebral cortex morphology |
abnormal neocortex morphology |
thickened cerebral cortex |
abnormal nervous system tract morphology |
decreased dopaminergic neuron number |
increased neuronal precursor cell number |
abnormal synapse morphology |
abnormal asymmetric synapse morphology |
abnormal postsynaptic density morphology |
abnormal synaptic vesicle number |
ectopic neuron |
abnormal spinal cord morphology |
abnormal spinal cord motor column morphology |
abnormal synaptic vesicle clustering |
abnormal synaptic vesicle recycling |
abnormal sensorimotor gating |
impaired synaptic plasticity |
abnormal CNS synaptic transmission |
abnormal excitatory postsynaptic potential |
enhanced long-term potentiation |
decreased miniature excitatory postsynaptic current frequency |
abnormal prepulse inhibition |
decreased neurotransmitter release |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
Cdh2em1Obir/Cdh2em1Obir | |||||||||||||||||||||||||||||||
Cdh2Gt(OST49160)Lex/Cdh2Gt(OST49160)Lex | |||||||||||||||||||||||||||||||
Cdh2tm1.1Ayki/Cdh2tm1.1Ayki | * | ||||||||||||||||||||||||||||||
Cdh2tm1Hyn/Cdh2tm1Hyn | |||||||||||||||||||||||||||||||
Cdh2tm1Glr/Cdh2tm1Glr Olig2tm1(cre)Tmj/Olig2+ (conditional) |
|||||||||||||||||||||||||||||||
Cdh2tm1Glr/Cdh2tm1Glr Emx1tm1(cre)Krj/Emx1+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/28/2024 MGI 6.13 |
|
|