Symbol
Name
ID

Camk2b
calcium/calmodulin-dependent protein kinase II, beta
MGI:88257

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Lower limb spasticity

Cerebellar atrophy

Ataxia

Athetoid cerebral palsy

Vocal cord paralysis

Reduced eye contact

Absent speech

Delayed speech and language development

Irritability

Autistic behavior

Aggressive behavior

Bruxism

Intellectual disability

Sleep abnormality

Dyskinesia

Inability to walk

Hyperkinetic movements

Developmental regression

Global developmental delay

Persistent head lag

Seizure

Bilateral tonic-clonic seizure

Focal impaired awareness seizure

Atonic seizure

Disease(s) Associated with CAMK2B

autosomal dominant intellectual developmental disorder 54

Mouse Phenotypes		nervous system phenotype	abnormal synaptic plasticity	abnormal long-term potentiation	reduced long-term potentiation	decreased prepulse inhibition	abnormal long-term depression
Availability	Mouse Genotype	nervous system phenotype	abnormal synaptic plasticity	abnormal long-term potentiation	reduced long-term potentiation	decreased prepulse inhibition	abnormal long-term depression
	Camk2b^tm1.1Ksak/Camk2b^tm1.1Ksak	*
	Camk2b^tm1Yelg/Camk2b^tm1Yelg	*
	Camk2b^tm2.1Yelg/Camk2b^tm2.1Yelg	*
	Camk2b^{tm1b(EUCOMM)Hmgu}/Camk2b⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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