Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
Darker colors indicate more annotations |
Human Phenotypes | Cerebellar hemorrhage |
Anorexia |
Small intestine carcinoid |
Cerebellar calcifications |
Astrocytoma |
Abnormal cranial nerve morphology |
Hydrocephalus |
Cerebellar cyst |
Spinal cord tumor |
Medulloblastoma |
Cerebellar medulloblastoma |
Neuroblastoma |
Ataxia |
Cerebellar ataxia associated with quadrupedal gait |
Dysmetria |
Progressive cerebellar ataxia |
Intention tremor |
Increased intracranial pressure |
Irritability |
Lethargy |
Cognitive impairment |
Abnormal brain FDG positron emission tomography |
Headache |
Global developmental delay |
Disease(s) Associated with APC | ||||||||||||||||||||||||
familial adenomatous polyposis 1 | ||||||||||||||||||||||||
medulloblastoma | ||||||||||||||||||||||||
pancreatic cancer |
Mouse Phenotypes | abnormal neural tube morphology |
abnormal floor plate morphology |
abnormal brain development |
abnormal hindbrain development |
absent midbrain |
absent forebrain |
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Availability | Mouse Genotype | ||||||
Apctm3Mmt/Apctm3Mmt | |||||||
ApcMin/Apctm1Tno | |||||||
Apctm1.1Tno/Apctm1Tno |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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