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Symbol
Name
ID
Agrn
agrin
MGI:87961
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Easy fatigability
Disease(s) Associated with AGRN
congenital myasthenic syndrome 8

Mouse Phenotypes
nervous system phenotype
abnormal innervation
abnormal innervation pattern to muscle
decreased CNS synapse formation
abnormal axon morphology
abnormal neuromuscular synapse morphology
failure of neuromuscular synapse presynaptic differentiation
increased post-tetanic potentiation
abnormal paired-pulse inhibition
Availability Mouse Genotype
AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg
Agrnnmf380/Agrnnmf380 * !
Agrntm1Jrs/Agrntm1Jrs *
Agrntm3Jrs/Agrntm3Jrs
Agrntm4Jrs/Agrntm4Jrs
Agrntm5Jrs/Agrntm5Jrs *
Agrntm1Rwb/Agrntm1Rwb
Tg(Pax3-cre)1Joe/0  (conditional)
Agrntm1Rwb/Agrntm1Rwb
Tg(Tek-cre)1Ywa/?  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory