Symbol Name ID |
Chrnb2
cholinergic receptor nicotinic beta 2 subunit MGI:87891 |
Darker colors indicate more annotations |
Human Phenotypes | Involuntary movements |
Increased theta frequency activity in EEG |
Interictal epileptiform activity |
EEG with focal spikes |
Depression |
Anxiety |
Psychotic mentation |
Suicidal ideation |
Atypical behavior |
Attention deficit hyperactivity disorder |
Motor stereotypy |
Cognitive impairment |
Intellectual disability, mild |
Somnambulism |
Confusional arousal |
NREM parasomnia |
Paroxysmal dystonia |
Seizure |
Bilateral tonic-clonic seizure |
Focal hyperkinetic seizure |
Nocturnal seizures |
Disease(s) Associated with CHRNB2 | |||||||||||||||||||||
autosomal dominant nocturnal frontal lobe epilepsy | |||||||||||||||||||||
autosomal dominant nocturnal frontal lobe epilepsy 3 |
Mouse Phenotypes | seizures |
increased susceptibility to induction of seizure by inducing agent |
abnormal brain morphology |
abnormal superior colliculus morphology |
abnormal lateral geniculate nucleus morphology |
abnormal nervous system electrophysiology |
abnormal brain wave pattern |
abnormal nicotine-mediated receptor currents |
|
Availability | Mouse Genotype | ||||||||
Chrnb2tm1.1Cont/Chrnb2tm1.1Cont | |||||||||
Chrnb2tm1Jpc/Chrnb2tm1Jpc | |||||||||
Chrnb2tm1Mdb/Chrnb2tm1Mdb | |||||||||
Chrnb2tm1.1Cont/Chrnb2+ | |||||||||
Tg(Prnp-tTA)F959Sbp/0 Tg(tetO-Chrnb2*V287L)H3Gica/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/28/2024 MGI 6.13 |
![]() |
|